Behavioral genetics has as its goal the discovery of genes that play a significant causal role in complex phenotypes that are socially relevant such a parenting, aggression, psychiatric disorders, intelligence, and even race. In this article, I present the stories of the discoveries of three such important phenotypes: maternal nurturing behavior and the c-fosB gene; intelligence and phenylketonuria (PKU); and pair-bonding and monogamy (vasopressin and oxytocin) and show that the reality is considerably more complex than often portrayed. These accounts also lay bare some fundamental misconceptions of this field in which genes hold a privileged place and inherently subjective phenomena are mistakenly objectified.

The development of genomics has dramatically expanded the scope of genetic research, and collections of genetic biosamples have proliferated in countries with active genomics research programs. In this essay, we consider a particular kind of collection, national biobanks. National biobanks are often presented by advocates as an economic "resource" that will be used by both basic researchers and academic biologists, as well as by pharmaceutical diagnostic and clinical genomics companies. Although national biobanks have been the subject of intense interest in recent social science literature, most prior work on this topic focuses either on bioethical issues related to biobanks, such as the question of informed consent, or on the possibilities for scientific citizenship that they make possible. We emphasize, by contrast, the economic aspect of biobanks, focusing specifically on the way in which national biobanks create biovalue. Our emphasis on the economic aspect of biobanks allows us to recognize the importance of what we call clinical labor—that is, the regularized, embodied work that members of the national population are expected to perform in their role as biobank participants—in the creation of biovalue through biobanks. Moreover, it allows us to understand how the technical way in which national biobanks link clinical labor to databases alters both medical and popular understandings of risk for common diseases and conditions.

In this article, we develop an approach for the moral assessment of research and development (R & D) networks on the basis of the reflective equilibrium approach proposed by Rawls and Daniels. The reflective equilibrium approach aims at coherence between moral judgments, principles, and background theories. We use this approach because it takes seriously the moral judgments of the actors involved in R & D, whereas it also leaves room for critical reflection about these judgments. It is shown that two norms, namely reflective learning and openness and inclusiveness, which are used in the literature on policy and technological networks, contribute to achieving a justified overlapping consensus. We apply the approach to a case study about the development of an innovative sewage treatment technology and show how in this case the two norms are or could be instrumental in achieving a justified overlapping consensus on relevant moral issues.

Science and technology studies (STS) analyses of emerging forms of treatment often result in the detailed display of complexities and at times lead to explicit critiques of particular healthcare practices. Simultaneously, there seems to be an increasing interest in exploring more experimental engagements by STS researchers in the proactive construction of such practices. In this article, I explore the relevance of experimental interventions in health care practices for both these care practices and for issues of the normativity of STS research. By analyzing my involvement in changes in the practice of hemophilia home treatment, I indicate how this care practice was reconfigured, partly by drawing on STS insights on the issue of compliance. I also claim that experimenting with forms of "artful contamination" allow STS researchers to do normativity in the practices they engage with. Such practices of interventionist STS research may be of value for refiguring debates in which constructivism has been accused of being normatively deficient. This may make interventionist STS research a fruitfully risky business.

The World Trade Organization (WTO) has been the target of social justice activists since its inception in 1994, with many seeking to reshape or rescind the WTO agreements. This article instead explores possible interventions into WTO adjudication by compelling the reinterpretation of existing WTO documents. Such an approach can take several forms: mobilizing professional expertise, engaging technical standards, and constructing companion regimes. Using the recent United States/European Community genetically modified organisms (GMO) case as a reference point, this article explores opportunities for implementing the last two strategies. The Codex Alimentarius, an international food standards regime, seems to provide a particularly promising location for reconstructing WTO risk and governance procedures. The Cartagena Biosafety Protocol, an international environmental regime, deeply challenges narrow readings of WTO texts but may not have enough legal force in the WTO. These alternative locations for intervention hold promise and risks for activists seeking international justice in environment, food, and trade.

In light of arguments that citizen science has the potential to make environmental knowledge and policy more robust and democratic, this article inquires into the factors that shape the ability of citizen science to actually influence scientists and decision makers. Using the case of community-based air toxics monitoring with "buckets," it argues that citizen science’s effectiveness is significantly influenced by standards and standardized practices. It demonstrates that, on one hand, standards serve a boundary-bridging function that affords bucket monitoring data a crucial measure of legitimacy among experts. On the other hand, standards simultaneously serve a boundary-policing function, allowing experts to dismiss bucket data as irrelevant to the central project of air quality assessment. The article thus calls attention to standard setting as an important site of intervention for citizen science-based efforts to democratize science and policy.

Thinkers from a variety of fields analyze the roles of imaging technologies in science and consider their implications for many issues, from our conception of selfhood to the authority of science. In what follows, I encourage scholars to develop an applied philosophy of imaging, that is, to collect these analyses of scientific imaging and to reflect on how they can be made useful for ongoing scientific work. As an example of this effort, I review concepts developed in Don Ihde’s phenomenology of technology and refigure them for use in the analysis of scientific practice. These concepts are useful for drawing out the details of the interpretive frameworks scientists bring to laboratory images. Next, I apply these ideas to a contemporary debate in neurobiology over the interpretation of images of neurons which have been frozen at the moment of transmitter release. This reveals directions for further thought for the study of neurotransmission.

Since its introduction in the 1980s, use of the innovation systems (IS) conceptual approach has been growing, particularly on the part of national governments including, recently, the Hong Kong Government. In 2004, the Hong Kong Government set forth a "new strategy" for innovation and technology policy making. Because it marked a significant break from the past (characterized by a laissez-faire Government attitude), it was necessary to convince a wider audience to accept this new strategy, a strategy that included the IS conceptual approach. Adopting a science and technology studies (S&TS) perspective, I show how the IS conceptual approach is being used as a rhetorical resource by the Hong Kong Government in its innovation and technology policy making in an effort to persuade its perceived audience of the efficacy of its new strategy for its policies—policies that are in fact unrelated to the basic precepts of the IS conceptual approach. The case provides a cautionary tale in the ways in which policy makers transform scholarly work and scientific discovery into rhetorical instruments in support of a political agenda.

The emergence of the global administrative sector and its new forms of knowledge production, expert rationality, and standardization, remains an understudied topic in science studies. Using a coproductionist theoretical framework, we argue that the mutual construction of epistemic and legal authority across international organizations has been critical for constituting and stabilizing a global regime for the regulation of food safety. The authors demonstrate how this process has also given rise to an authoritative framework for risk analysis touted as "scientifically rigorous" but embodying particular value choices regarding health, environment, and the dispensation of regulatory power. Finally, the authors trace how enrollment of the Codex Alimentarius in World Trade Law has heightened institutional dilemmas around legitimacy and credibility in science advice at the global level. Taken together, the case illustrates the importance of attending to the iterative construction of law and science in the constitution of new global administrative regimes.

Participation of a broad variety of actors in decision-making processes has become an important issue in science and technology policy. Many authors claim the involvement of stakeholders and of the general public to be a core condition for legitimate and sustainable decision making. In the last decades, a wide spectrum of procedures has been developed to realize biotechnological citizenship. These procedures, composed of multiactor arenas, are either located in close relation to the system of politics, or, as in the case of administrative decision making, more closely to the system of law. In the latter case, a problematic constellation arises. Here, law and science can build a technoscientific normativity that systematically excludes political discourse. The law, although intending to provide for political freedom and citizenship rights, at the end appears to be an "iron cage" for political communication.

Since the 1980s the concept of ANT has remained unsettled. ANT has continuously been critiqued and hailed, ridiculed and praised. It is still an open question whether ANT should be considered a theory or a method or whether ANT is better understood as entailing the dissolution of such modern "genres". In this paper the authors engage with some important reflections by John Law and Bruno Latour in order to analyze what it means to "do ANT," and (even worse), doing so after "doing ANT on ANT." In particular the authors examine two post-ANT case studies by Annemarie Mol and Marilyn Strathern and outline the notions of complexity, multiplicity, and fractality. The purpose is to illustrate the analytical consequences of thinking with post-ANT. The analysis offers insights into how it is possible to "go beyond ANT," without leaving it entirely behind.

This article explores the work-arounds through which an Enterprise Resource Planning (ERP) software system is implemented within an Australian University. We argue that while resistance is significant, the process of working around a technology can have ambiguous effects in terms of how users—in this case academics—are governed and govern themselves. Drawing upon Andrew Barry's Foucauldian-inspired work on "technological zones," we show how attempts to work-around the ERP contributed to the creation of an alternative technological zone based on cultural discourses of academic freedom aimed at resisting the standardized programs of action inscribed within the university-wide ERP. However, we demonstrate also that these work-arounds resulted in a partial convergence with the university’s advanced liberal objectives of going online to become a globally competitive university. We conclude that more research needs to be conducted into the multiple and ambiguous effects of work-arounds in the practice of governing.